As President, it is a great honor for me to organize the 47th Annual Meeting of the Japanese Society of Toxicology (JSOT). This year's annual meeting will be held just before the 2020 Tokyo Olympic and Paralympic games. It will be a great opportunity to further advance internationalization, which is currently promoted by the JSOT. At the same time, I am working hard to promote the academic progress of the JSOT in Japan and abroad in an attractive manner. I am keenly aware that holding this year’s annual meeting is a very important endeavor for our JSOT.
The current situation of toxicology is that newly developed technologies, such as genome editing, have been incorporated into toxicology research immediately after they were established. Additionally, with the development of other technologies such as nanotechnology, the number of substances subjected to toxicology research has increased. Thus, the fields involved in toxicology research have diversified, and the methods of research have become more complex. This indicates that risk assessment and risk management issues requiring future toxicological approaches cannot be solved using a single technique, even if modern toxicological approaches are used. Furthermore, all the traditional problems of risk management have not yet been solved. For example, the development of management methods for more than hundreds of thousands of existing chemical substances without toxicity information is still progressing toward achieving a sustainable developmental society.
The concept of “one toxicology” was proposed by Dr. Val Beasley in 2009, and it involves integrating medicine, veterinary medicine, and environmental toxicology in order to achieve “one health.” I think this concept is necessary to protect health of the entire “living” environment, including humans and animals, while decreasing the risks from developing new technologies. That is, all toxicological knowledge must be merged at every level, from the individual to the cellular and molecular levels, from in vivo to in vitro and in silico toxicology, and from epidemiological and clinical studies to nonclinical studies. The concept, which was proposed 10 years ago, is now being recognized as a concept in which various research fields converge because of the development of new technologies that cross academic and technological fields. At the same time, it considers the meaning of internationalization promoted by the JSOT, which is a suitable theme for the 2020 Annual Meeting.
Sendai was selected as the venue for the 47th Annual Meeting of the JSOT because it has convenient access from the Tokyo area, and participants can avoid facing extensive preparations of the Olympic/Paralympic games. Sendai is also the best place to feel the harmony of “one toxicology” with the progress of the JSOT towards internationalization immediately before the Tokyo 2020 Olympic/Paralympic games. I hope you will take this opportunity to experience the new fusion and internationalization of toxicology at the 47th Annual Meeting of the JSOT in Sendai.
Akihiko Hirose, Ph.D.
President of 47JSOT